Potential Research Project
The solution properties of eye lens proteins are being studied to aid in understanding of the molecular causes of cataract disease. Static light scattering will be used to measure the molecular weight and second virial coefficient (a measure of the strength of inter-particle interactions) of bovine eye lens protein alpha-crystallin as a function of pH and ionic strength. Alpha/gamma interactions as well as alpha-A and alpha-B subunit composition will be explored. |