Paul Craig

Head, School of Chemistry and Materials Sciences, Professor

Website

Contact Information

OfficeGOS 2116
Phone(585) 475-6145
Fax(585) 475-7800
Emailpaul.craig@rit.edu


B.S., 1979 Oral Roberts University

Ph.D., 1985 University of Michigan

Research Interests

  • Computational Biochemistry
  • Educational Uses of Molecular Visualization
  • Structural Biology
  • Analytical Chemistry
  • Proteomics

Selected Publications

Hanson, B.*, Westin, C.*, Rosa, M.*, Grier, A., Osipovitch, M., MacDonald, M.L.*, Dodge, G.*, Boli, P.M.*, Corwin, C.W.*, Kessler, H.*, McKay, T.*, Bernstein, H.J., Craig, P.A. Estimation of Protein Function Using Template-Based Alignment of Enzyme Active Sites. BMC Bioinformatics, accepted for publication.

Craig, P., Michel, L, Bateman, R. A Survey of Educational Uses of Molecular Visualization, Biochemistry and Molecular Biology Education41:193-205 (2013) DOI: 10.1002/bmb.20693.

Fisher, A.*, Sekera, E.*, Payne, J.*, Craig, P.A. Simulation of Two Dimensional Electrophoresis and Tandem Mass Spectrometry for Teaching Proteomics, Biochemistry and Molecular Biology Education, 40:393-399 (2012), DOI: 10.1002/bmb.20651.

Cody, J.A., Craig, P.A., Loudermilk, A.D.*, Yacci, P.M., Frisco, S.L.*, Milillo, J.R.*  Design and Implementation of a Self-Directed Stereochemistry Lesson Using Embedded Virtual Three-Dimensional Images in a Portable Document Format. Journal of Chemical Education, 89:29-33 (2012), DOI: 10.1021/ed100441f.

Michel, L.V., Kalmeta, B.*, McCreary, M., Snyder, J.*, Craig, P.A., Pichichero, M.E. Vaccine candidate P6 of nontypable Haemophilus influenzae is not a transmembrane protein based on protein structural analysis. Vaccine, 29: 1624-1627 (2011).

Mottarella, S.E.*, Rosa, M.*, Bangura, A.*, Bernstein, H., Craig, P.A. ConSCRIPT: A Rasmol to PyMOL Script Convertor.  Biochemistry and Molecular Biology Education, 38: 419-422 (2010).

Craig, P.A., Federici, E.*, Buehler, M. Instructing Students in Academic Integrity, accepted for publication, Journal of College Science Teaching, 40:50-55 (2010).

Kim, T.D., Craig, P.A. Introducing Proteomics in the Undergraduate Curriculum: A Simple 2D Gel Electrophoresis Exercise with Serum Proteins, accepted for publication, Biochemistry and Molecular Biology Education, 38: 29-34 (2010).

Bernstein, H. J., Craig, P. A., Efficient Molecular Surface Rendering by Linear-Time Pseudo-Gaussian Approximation to Lee-Richards Surfaces (PGALRS), Journal of Applied Crystallography, 43: 356-361 (2010).

Grell, L.*, Parkin, C.*, Slatest, L., Craig, P.A., EZ-Viz, a tool for simplifying molecular viewing in PyMOL, Biochemistry and Molecular Biology Education, 34: 402-407 (2006).

Yang, P., Craig, P. A., Goodsell, D., Bourne, P. E. BioEditor - Simplifying Macromolecular Structure Annotation, Bioinformatics 19: 897-898 (2003).

Craig, P.A. BioMoleculesAlive.org - The Biochemistry and Molecular Biology Digital Library, Biochemistry and Molecular Biology Education 31:73-74 (2003).

Craig, P. A. A project-oriented biochemistry laboratory course. Journal of Chemical Education 76: 1130-1135 (1999).

W. Schramm, R. H. Smith, P. A. Craig, H. E. Grates, Testosterone Concentration is Increased in Whole Saliva, but not in Ultrafiltrate after Toothbrushing, Clinical Chemistry. 39:519-521 (1993).

W. Schramm, P. A. Craig, R. H. Smith and G. E. Berger, Cocaine and Benzoylecgonine in Saliva, Serum, and Urine, Clinical Chemistry, 39:481-487 (1992).

W. Schramm, R. H. Smith, P. A. Craig and D. A. Kidwell, Drugs of Abuse in Saliva: A Review, Journal of Analytical Toxicology, 16: 1-9 (1992).

S. Olson, I. Bjork, R. Sheffer, P. A. Craig, J. D. Shore and J. Choay, Role of the Antithrombin-binding Pentasaccharide in Heparin Acceleration of Antithrombin-proteinase Reactions, Journal of Biological Chemistry., 267, 12528-38 (1992).

W. Schramm, R. H. Smith, P. A. Craig, S-W Paek and H-H Kuo, Determination of Free Progesterone in an Ultrafiltrate of Saliva Collected in Situ, Clinical Chemistry, 36, 1488-1493 (1990).

W. Schramm, R. H. Smith, T. M. Jackson, P. A. Craig, H. E. Gates and L. L. Minton, Rapid Solid-phase Immunoassay for 6-keto Prostaglandin F1α on Microplates, Clinical Chemistry, 36, 509-514 (1990).

P. A. Craig and E. E. Dekker, The Sulfhydryl Content of L-threonine Dehydrogenase From Escherichia coli K-12: Relation to Catalytic Activity and Mn2+ Activation, Biochimica Biophysica Acta, 1037, 30-38 (1990).

P. A. Craig, S. T. Olson and J. D. Shore, Transient Kinetics of Heparin-catalyzed Protease Inactivation by Antithrombin III: Characterization of Assembly, Product Formation and Heparin Dissociation Steps in the Factor Xa Reaction, Journal of Biological Chemistry, 26 2, 5452-5461 (1989).

P. E. Bock, P. A. Craig, S. T. Olson and P. Singh, Isolation of Human Blood Coagulation α-factor Xa by Soybean Trypsin Inhibitor-sepharose Chromatography and its Active-site Titration with Fluorescein Mono-p-guanidinobenzoate, Archives of Biochemistry and Biophysics, 273, 375-388 (1989).

J. D. Shore, S. T. Olson, P. A. Craig, J. Choay and I. Bjork, Kinetics of Heparin Action, Annals of the New York Academy of Science., 556, 75-80 (1989).

P. A. Craig and E. E. Dekker, Cd2+ Activation of L-threonine Dehydrogenase From Escherichia coli K-12, Biochimica Biophysica Acta, 957, 222-229 (1988).

P. A. Craig and E. E. Dekker, L-Threonine Dehydrogenase From E. coli K-12:Thioldependent Activation by Mn2+, Biochemistry, 25, 1870-1876 (1986).

 

 

Grant Support

1R15GM078077-01 Bernstein (PI) 8/1/2006 - 1/31/2011
NIH/NIGMS
Structural Biology Extensible Visualization Scripting Language (SBEVSL)
Creation of a common molecular graphics scripting language.
Role: Co-Investigator

3R15GM078077-01S Bernstein (PI) 6/1/2009 - 1/31/2011
NIH/NIGMS
Diversity Supplement to Structural Biology Extensible Visualization Scripting Language (SBEVSL)
Creation of a common molecular graphics scripting language.
Role: Co-Investigator

2R15GM078077-02 Bernstein (PI) 9/1/2011 - 8/31-2014
NIH/NIGMS
Algorithmic assignment of probable function to proteins of previously unknown function
Role: Co-Investigator

3R15GM078077-02S1 Bernstein (PI) 11/1/2011 - 8/31/2014
Diversity Supplement to Algorithmic assignment of probable function to proteins of previously unknown function
Role: Co-Investigator

1050590 Maggelakis (PI) 9/1/2011 - 8/31/2013
NSF MSP
Boundary Crossing Teams in Support of Math and Science Excellence inOur School Systems
Role: Senior Personnel - Disciplinary Content Advisor