Publications

Journal

Journal

  • Forouzandeh, Farzad, and David A. Borkholder. "Microtechnologies for inner ear drug delivery." Current Opinion in Otolaryngology & Head and Neck Surgery 28, no. 5 (2020): 323-328.
    DOI:10.1097/MOO.0000000000000648
  • Forouzandeh, Farzad, Nuzhet N. Ahamed, Meng-Chun Hsu, Joseph P. Walton, Robert D. Frisina, and David A. Borkholder. "A 3D-Printed Modular Microreservoir for Drug Delivery." Micromachines 11, no. 7 (2020): 648.
    DOI:10.3390/mi11070648 Open source
  • Moudgalya, S.S., Wilson, K., Zhu, X., Budzevich, M.M., Walton, J.P., Cahill,N.D., Frisina, R.D., Borkholder, D.A.,"Cochlear Pharmacokinetics – Micro-Computed Tomography and Learning-Prediction Modeling for Transport Parameter Determination." Hearing Research 380 (2019): 46-59.
    DOI: 10.1016/j.heares.2019.05.009 Open source
  • Forouzandeh, Farzad, Xiaoxia Zhu, Ahmed Alfadhel, Bo Ding, Joseph P. Walton, Denis Cormier, Robert D. Frisina, and David A. Borkholder. "A nanoliter resolution implantable micropump for murine inner ear drug delivery." Journal of Controlled Release 298 (2019): 27-37.
    DOI: 10.1016/j.jconrel.2019.01.032  Open source
  • Mahajan, Chaitanya G., Ahmed Alfadhel, Mark Irving, Bruce E. Kahn, David A. Borkholder, Scott A. Williams, and Denis Cormier. "Magnetic Field Patterning of Nickel Nanowire Film Realized by Printed Precursor Inks." Materials 12, no. 6 (2019): 928.
    DOI: 10.3390/ma12060928  Open source
  • Conn, Nicholas J., Karl Q. Schwarz, and David A. Borkholder. "In-Home Cardiovascular Monitoring System for Heart Failure: Comparative Study." JMIR mHealth and uHealth 7, no. 1 (2019): e12419.
    DOI: 10.2196/12419  Open source
  • Ouyang, Jing, Denis Cormier, and David A. Borkholder. "Piezoelectric Property Enhancement of PZT Thick Film via Pulsed Flash Poling during Sintering." ACS Applied Energy Materials 2, no. 1 (2018): 338-343.
    DOI: 10.1021/acsaem.8b01337
  • Frisina, R. D., M. Budzevich, X. Zhu, G. V. Martinez, J. P. Walton, and D. A. Borkholder. "Animal model studies yield translational solutions for cochlear drug delivery." Hearing Research 368 (2018): 67-74.
    DOI: 10.1016/j.heares.2018.05.002
  • Alfadhel, Ahmed, Jing Ouyang, Chaitanya G. Mahajan, Farzad Forouzandeh, Denis Cormier, and David A. Borkholder. "Inkjet printed polyethylene glycol as a fugitive ink for the fabrication of flexible microfluidic systems." Materials & design 150 (2018): 182-187.
    DOI: 10.1016/j.matdes.2018.04.013
  • Hsu, Meng-Chun, Ahmed Alfadhel, Farzad Forouzandeh, and David A. Borkholder. "Biocompatible magnetic nanocomposite microcapsules as microfluidic one-way diffusion blocking valves with ultra-low opening pressure." Materials & design150 (2018): 86-93.
    DOI: 10.1016/j.matdes.2018.04.024 
  • Conn, Nicholas J., Karl Q. Schwarz, and David A. Borkholder. "Nontraditional electrocardiogram and algorithms for inconspicuous in-home monitoring: comparative study." JMIR mHealth and uHealth 6, no. 5 (2018): e120.
    DOI: 10.2196/mhealth.9604  Open source
  • Antoine, Michelle W., Xiaoxia Zhu, Marianne Dieterich, Thomas Brandt, Sarath Vijayakumar, Nicholas McKeehan, Joseph C. Arezzo et al. "Early uneven ear input induces long-lasting differences in left–right motor function." PLoS biology16, no. 3 (2018): e2002988.
    DOI: 10.1371/journal.pbio.2002988  Open source
  • Liberson, A. S., Y. Seyed Vahedein, and D. A. Borkholder. "Application of Variational Principle to Form Reduced Fluid-Structure Interaction Models in Bifurcated." Journal of Fluid Flow, Heat and Mass Transfer (JFFHMT) 4, no. 1 (2017): 1-9.
    DOI: 10.11159/jffhmt.2017.001  Open source
  • Lillie, Jeffrey S., Alexander S. Liberson, and David A. Borkholder. "Improved blood pressure prediction using systolic flow correction of pulse wave velocity." Cardiovascular engineering and technology 7, no. 4 (2016): 439-447.
    DOI: 10.1007/s13239-016-0281-y  Open source
  • Liberson, Alexander S., Jeffrey S. Lillie, Steven W. Day, and David A. Borkholder. "A physics based approach to the pulse wave velocity prediction in compliant arterial segments." Journal of biomechanics 49, no. 14 (2016): 3460-3466.
    DOI: 10.1016/j.jbiomech.2016.09.013
  • Johnson, Dean, and David Borkholder. "Towards an implantable, low flow micropump that uses no power in the blocked-flow state." Micromachines 7, no. 6 (2016): 99.
    DOI: 10.3390/mi7060099  Open source
  • Lillie, Jeffrey S., Alexander S. Liberson, and David A. Borkholder. "Quantification of hemodynamic pulse wave velocity based on a thick wall multi-layer model for blood vessels." Journal of Fluid Flow, Heat and Mass Transfer 3 (2016).
    DOI: 10.11159/jffhmt.2016.007  Open source
  • Ouyang, Jing, Denis Cormier, Scott A. Williams, and David A. Borkholder. "Photonic sintering of aerosol jet printed lead zirconate titanate (PZT) thick films." Journal of the American Ceramic Society 99, no. 8 (2016): 2569-2577.
    DOI: 10.1111/jace.14272
  • Lillie, Jeffrey S., Alexander S. Liberson, Doran Mix, Karl Q. Schwarz, Ankur Chandra, Daniel B. Phillips, Steven W. Day, and David A. Borkholder. "Pulse wave velocity prediction and compliance assessment in elastic arterial segments." Cardiovascular engineering and technology 6, no. 1 (2015): 49-58.
    DOI: 10.1007/s13239-014-0202-x  Open source
  • Getpreecharsawas, Jirachai, James L. McGrath, and David A. Borkholder. "The electric field strength in orifice-like nanopores of ultrathin membranes." Nanotechnology 26, no. 4 (2015): 045704.
    DOI: 10.1088/0957-4484/26/4/045704  Open source
  • Kelly, Matthew R., Vincent J. Amuso, David A. Eddins, and David A. Borkholder. "The focal index as a singular metric for beamforming effectiveness." The Journal of the Acoustical Society of America 136, no. 5 (2014): 2654-2664.
    DOI: 10.1121/1.4896465 
  • Liberson, Alexander S., Jeffrey S. Lillie, and David A. Borkholder. "Numerical solution for the boussinesq type models with application to arterial flow." Journal of Fluid Flow, Heat and Mass Transfer (JFFHMT) 1 (2014): 9-15.
    DOI: 10.11159/jffhmt.2014.002  Open source
  • Haghpanahi, Masoumeh, and David A. Borkholder. "Fetal QRS extraction from abdominal recordings via model-based signal processing and intelligent signal merging." Physiological measurement 35, no. 8 (2014): 1591.
    DOI: 10.1088/0967-3334/35/8/1591  Open source
  • Borkholder, David A., Xiaoxia Zhu, and Robert D. Frisina. "Round window membrane intracochlear drug delivery enhanced by induced advection." Journal of controlled release174 (2014): 171-176.
    DOI: 10.1016/j.jconrel.2013.11.021  Open source
  • Snyder, Jessica L., Jirachai Getpreecharsawas, David Z. Fang, Thomas R. Gaborski, Christopher C. Striemer, Philippe M. Fauchet, David A. Borkholder, and James L. McGrath. "High-performance, low-voltage electroosmotic pumps with molecularly thin silicon nanomembranes." Proceedings of the National Academy of Sciences 110, no. 46 (2013): 18425-18430.
    DOI: 10.1073/pnas.1308109110  Open source
  • Haghpanahi, Masoumeh, Miriam B. Gladstone, Xiaoxia Zhu, Robert D. Frisina, and David A. Borkholder. "Noninvasive technique for monitoring drug transport through the murine cochlea using micro-computed tomography." Annals of biomedical engineering 41, no. 10 (2013): 2130-2142.
    DOI: 10.1007/s10439-013-0816-4  Open source
  • Pararas, Erin E. Leary, David A. Borkholder, and Jeffrey T. Borenstein. "Microsystems technologies for drug delivery to the inner ear." Advanced drug delivery reviews 64, no. 14 (2012): 1650-1660.
    DOI: 10.1016/j.addr.2012.02.004  Open source
  • Johnson, Dean G., Robert D. Frisina, and David A. Borkholder. "In-plane biocompatible microfluidic interconnects for implantable microsystems." IEEE Transactions on Biomedical Engineering 58, no. 4 (2011): 943-948.
    DOI: 10.1109/TBME.2010.2098031  Open source
  • Borkholder, David A., Xiaoxia Zhu, Brad T. Hyatt, Alfredo S. Archilla, William J. Livingston III, and Robert D. Frisina. "Murine intracochlear drug delivery: reducing concentration gradients within the cochlea." Hearing research 268, no. 1-2 (2010): 2-11.
    DOI: 10.1016/j.heares.2010.04.014  Open source
  • Borkholder, David A. "State-of-the-art mechanisms of intracochlear drug delivery." Current opinion in otolaryngology & head and neck surgery 16, no. 5 (2008): 472-477.
    DOI: 10.1097/MOO.0b013e32830e20db    Open source
  • Raisi, Fariba, Phillip Belgrader, David A. Borkholder, Amy E. Herr, Gregory J. Kintz, Farzad Pourhamadi, Michael T. Taylor, and M. Allen Northrup. "Microchip isoelectric focusing using a miniature scanning detection system." Electrophoresis 22, no. 11 (2001): 2291-2295.
    DOI: 10.1002/1522-2683(20017)22:11<2291::AID-ELPS2291>3.0.CO;2-A  Open source
  • Belgrader, Phillip, Margaret Okuzumi, Farzad Pourahmadi, David A. Borkholder, and M. Allen Northrup. "A microfluidic cartridge to prepare spores for PCR analysis." Biosensors and bioelectronics 14, no. 10-11 (2000): 849-852.
    DOI: 10.1016/S0956-5663(99)00060-3 
  • Pancrazio, Joseph J., J. P. Whelan, David A. Borkholder, W. Ma, and David A. Stenger. "Development and application of cell-based biosensors." Annals of biomedical engineering 27, no. 6 (1999): 697-711.
    DOI: 10.1114/1.225  Open source
  • Pancrazio, Joseph J., Paul P. Bey Jr, David S. Cuttino, Julian K. Kusel, David A. Borkholder, Kara M. Shaffer, Gregory TA Kovacs, and David A. Stenger. "Portable cell-based biosensor system for toxin detection." Sensors and Actuators B: Chemical 53, no. 3 (1998): 179-185.
    DOI: 10.1016/S0925-4005(98)00340-2 
  • Pancrazio, Joseph J., Paul P. Bey Jr, Arash Loloee, SubbaRao Manne, Hui-Chuan Chao, Lorn L. Howard, W. Milton Gosney et al. "Description and demonstration of a CMOS amplifier-based-system with measurement and stimulation capability for bioelectrical signal transduction." Biosensors and Bioelectronics 13, no. 9 (1998): 971-979.
    DOI: 10.1016/S0956-5663(98)00006-2  Open source
  • Jung, D. R., D. S. Cuttino, J. J. Pancrazio, P. Manos, T. Cluster, R. S. Sathanoori, L. E. Aloi et al. "Cell-based sensor microelectrode array characterized by imaging x-ray photoelectron spectroscopy, scanning electron microscopy, impedance measurements, and extracellular recordings." Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films 16, no. 3 (1998): 1183-1188.
    DOI: 10.1116/1.581256
  • Borkholder, D. A., J. Bao, N. I. Maluf, E. R. Perl, and G. T. A. Kovacs. "Microelectrode arrays for stimulation of neural slice preparations." Journal of neuroscience methods 77, no. 1 (1997): 61-66.
    DOI: 10.1016/S0165-0270(97)00112-X 
  • Kewley, David T., Matthew D. Hills, David A. Borkholder, Ion E. Opris, Nadim I. Maluf, Christopher W. Storment, James M. Bower, and Gregory TA Kovacs. "Plasma-etched neural probes." Sensors and Actuators A: Physical 58, no. 1 (1997): 27-35.
    DOI: 10.1016/S0924-4247(97)80221-X 
  • Storment, Christopher W., David A. Borkholder, Victor Westerlind, John W. Suh, Nadim I. Maluf, and Gregory TA Kovacs. "Flexible, dry-released process for aluminum electrostatic actuators." Journal of Microelectromechanical Systems 3, no. 3 (1994): 90-96.
    DOI: 10.1109/84.311558  Open source
  • Owen, G., D. Borkholder, C. Knorr, D. A. Markle, and R. F. W. Pease. "Quarter‐micron lithography with a gapped Markle–Dyson system." Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena 12, no. 6 (1994): 3809-3813.
    DOI: 10.1116/1.587446 

Conference Proceedings

Conference Proceedings

  • Alfadhel, A., Ouyang, J., Cormier, D. and Borkholder, D.A., 2020, October. Enhanced Properties of Aerosol Jet Printed PZT: Towards Realizing Flexible Automotive Sensors. In 2020 IEEE Sensors (pp. 1-4). IEEE.
  • Moudgalya, Sanketh S., Nathan D. Cahill, and David A. Borkholder. "Deep Volumetric Segmentation of Murine Cochlear Compartments from Micro-Computed Tomography Images." In 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), pp. 1970-1975. IEEE, 2020.
  • Moudgalya, Sanketh S., Cahill, Nathan D., Borkholder, David A., "Deep Volumetric Segmentation of Murine Cochlear Compartments from Micro-Computed Tomography Images." 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC 2020), Montreal, Canada, July (2020).
  • Wei-yao Ku, Nicholas Conn, David Borkholder, and Ifeoma Nwogu. "Novel Biometrics: Analysis of an Unattended Health Monitoring System." In 2018 IEEE 9th International Conference on Biometrics Theory, Applications and Systems (BTAS), pp. 1-7. IEEE, 2018.
  • Farzad Forouzandeh, Ahmed Alfadhel, Xiaoxia Zhu, Joseph P. Walton, Denis R. Cormier, Robert D. Frisina, and David A. Borkholder. "A wirelessly controlled fully implantable microsystem for nano-liter resolution inner ear drug delivery." in Proc. 18th Solid-State Sensors, Actuators, and Microsystems Workshop, Hilton Head Island, SC, USA, 2018.
  • Liberson, A. S., Y. Seyed Vahedein, and D. A. Borkholder. "Variational Approach of Constructing Reduced Fluid-Structure Interaction Models in Bifurcated Networks." In Proceedings of the 2nd World Congress on Momentum, Heat and Mass Transfer, Barselona, pp. 6-8. 2017.
  • A.Liberson, J.Lillie, P.Koya, D.Borkholder. "Simulation of wave propagation through the bifurcated compliant arterial network." Proceedings of the 2nd International Conference on Fluid Flow, Heat and Mass Transfer Ottawa, Ontario, Canada, April 30 – May 1, 2015
  • Lillie, Jeffrey S., Alexander S. Liberson, and David A. Borkholder. "Pulse wave velocity prediction in multi-layer thick wall arterial segments." In Proceeding of the 2nd International Conference on Fluid Flow, Heat and Mass Transfer. Ottawa, Ca. 2015.
  • Ouyang, Jing, Anirudh R. Penmetcha, Denis Cormier, and David A. Borkholder. "Photonically Sintered PZT Energy Harvester." In ASME 2015 International Mechanical Engineering Congress and Exposition, pp. V010T13A024-V010T13A024. American Society of Mechanical Engineers, 2015.
  • Borkholder, D. A. "Concept to commercialization of a MEMS-based blast dosimetry system." In 2015 Transducers-2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), pp. 281-286. IEEE, 2015.
  • Haghpanahi, Masoumeh, Reza Sameni, and David A. Borkholder. "Scoring consensus of multiple ECG annotators by optimal sequence alignment." In 2014 36th annual international conference of the IEEE engineering in medicine and biology society, pp. 1855-1859. IEEE, 2014.
  • Conn, Nicholas J., and David A. Borkholder. "Wavelet based photoplethysmogram foot delineation for heart rate variability applications." In 2013 IEEE Signal Processing in Medicine and Biology Symposium (SPMB), pp. 1-5. IEEE, 2013.
  • Ostertag, Michael H., Matthew Kenyon, David A. Borkholder, General Lee, Uade da Silva, and Gary Kamimori. "The blast gauge™ system as a research tool to quantify blast overpressure in complex environments." In ASME 2013 International Mechanical Engineering Congress and Exposition, pp. V03AT03A017-V03AT03A017. American Society of Mechanical Engineers, 2013.
  • Haghpanahi, Masoumeh, and David A. Borkholder. "Fetal ECG extraction from abdominal recordings using array signal processing." In Computing in Cardiology 2013, pp. 173-176. IEEE, 2013.
  • Borkholder, David, and Nicholas Conn. “A Comparison of Reconstruction Methods for Compressed Sensing of the Photoplethysmogram”. Zenodo, 2013.
  • Johnson, D. G., J. Getpreecharsawas, S. Balasubramanian, A. Datar, D. Cormier, and D. A. Borkholder. "Hybrid MEMS: Extending micro manufacturing with direct write processes." In Technical Digest of Transducers Research Foundation Technologies for Future Micro-Nano Manufacturing Workshop. 2011.
  • Johnson, D. G., M. J. Waldron, R. D. Frisina, and D. A. Borkholder. "Implantable micropump technologies for murine intracochlear infusions." In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, pp. 6441-6444. IEEE, 2010.
  • Czernikowski, Roy S., Margaret B. Bailey, David A. Borkholder, Matthew M. Marshall, Alan H. Nye, and N. Richard Reeve. "RIT’s engineering honors program: Product innovation in a global Economy." In 2007 37th Annual Frontiers In Education Conference-Global Engineering: Knowledge Without Borders, Opportunities Without Passports, pp. T2A-9. IEEE, 2007.
  • Johnson, Dean G., Xiao Xia Zhu, Robert D. Frisina, and David A. Borkholder. "Micro-molded cannulae for intracochlear infusions in small rodents." In 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 6616-6619. IEEE, 2007.
  • Herr, A. E., J. I. Molho, R. Bharadwaj, J. C. Mikkelsen, J. G. Santiago, T. W. Kenny, D. A. Borkholder, and M. A. Northrup. "Miniaturized Isoelectric Focusing (µIEF) As a Component of a Multi-Dimensional Microfluidic System." In Micro Total Analysis Systems 2001, pp. 51-53. Springer, Dordrecht, 2001.
  • Belgrader, Phillip, Rekha Joshi, Jesus Ching, Sandy Zaner, David A. Borkholder, and M. Allen Northrup. "Real-time PCR Analysis on Nucleic Acids Purified from Plasma Using a Silicon Chip." In Micro Total Analysis Systems 2000, pp. 525-528. Springer, Dordrecht, 2000.
  • Herr, A. E., J. I. Molho, J. G. Santiago, T. W. Kenny, D. A. Borkholder, G. J. Kintz, P. Belgrader, and M. A. Northrup. "Miniaturized Capillary Isoelectric Focusing (cIEF): Towards a Portable High-Speed Separation Method." In Micro Total Analysis Systems 2000, pp. 367-370. Springer, Dordrecht, 2000.
  • Herr, Amy E., Joshua I. Molho, Juan G. Santiago, Thomas W. Kenny, David A. Borkholder, Gregory J. Kintz, Phillip Belgrader, and M. Allen Northrup. "Investigation of a Miniaturized Capillary Isoelectric Focusing (cIEF) System Using a Full-Field Detection Approach." In Solid State Sensor and Actuator Workshop, Hilton Head Island, SC, pp. 4-8. 2000.
  • Herr, Amy E., J. C. Mikkelsen, Juan G. Santiago, Thomas W. Kenny, D. A. Borkholder, and M. A. Northrup. "Electroosmotic flow suppression and its implications for a miniaturized full-field detection approach to capillary isoelectric focusing." In 2000 ASME International Mechanical Engineering Congress and Exposition, Orlando, FL. 2000.
  • Borkholder, David A., B. Derek DeBusschere, and Gregory TA Kovacs. "Hybrid biosensors: Harnessing living tissues for chem/bio warfare agent detection." Power 20 (1999): 10.
  • DeBusschere, B. D., A. M. Aravanis, A. J. Chruscinski, K. H. Gilchrist, D. A. Borkholder, B. K. Kobilka, and G. T. A. Kovacs. "Genetically engineered cell-based biosencors for specific agent classification." In Conference on Solid-state Sensors and Actuators, pp. 65-71. 1999.
  • DeBusschere, B. Derek, David A. Borkholder, and Gregory TA Kovacs. "System requirements for a portable cell based sensor." In Micro Total Analysis Systems’ 98, pp. 443-446. Springer, Dordrecht, 1998.
  • DeBusschere, B. D., D. A. Borkholder, and G. T. A. Kovacs. "Design of an integrated silicon-PDMS cell cartridge." In Proceedings of the Solid-State Sensor and Actuator Workshop, Hilton Head, South Carolina, pp. 8-11. 1998.
  • Borkholder, David, B. Derek DeBusschere, and Gregory Kovacs. "An approach to the classification of unknown biological agents with cell based sensors." (1998).
  • Kewley, David T., Matthew D. Hills, David A. Borkholder, Ion E. Opris, Nadim I. Maluf, Christopher W. Storment, James M. Bower, and Gregory TA Kovacs. "Plasma-etched neural probes." Sensors and Actuators A: Physical 58, no. 1 (1997)
  • Borkholder, D. A., I. E. Opris, N. I. Maluf, and G. T. A. Kovacs. "Planar electrode array systems for neural recording and impedance measurements." In Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 1, pp. 106-107. IEEE, 1996.
  • Borkholder, D. A., N. I. Maluf, and G. T. A. Kovacs. "Impedance imaging for hybrid biosensor applications." In Solid-State Sensor and Actuator Workshop, Hilton Head Island, SC. 1996.
  • Grenville, Andrew, Gerry Owen, Jeff A. Robinson, David Anthony Borkholder, Curtis W. Frank, Roger Fabian W. Pease, and David A. Markle. "Masks for Markle-Dyson optics." In 13th Annual BACUS Symposium on Photomask Technology and Management, vol. 2087, pp. 2-10. International Society for Optics and Photonics, 1994.
  • Storment, Christopher W., and David A. Borkholder. "Dry-released process for aluminum electrostatic actuators." In J. Microelectro-mechanical systems. 1994.

Conference

Conference

  • Moudgalya, Sanketh S., Cahill, Nathan D., Borkholder, David A., "Deep Volumetric Segmentation of Murine Cochlear Compartments from Micro-Computed Tomography Images." 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC 2020), Montreal, Canada, July (2020).
    DOI: 10.1109/EMBC44109.2020.9176596
  • Moudgalya, Sanketh S., Zhu, Xiaoxia, Budzevich, Mikalai M., Walton, Joseph P., Cahill, Nathan D.,  Frisina, Robert D., Borkholder,  David A., "Cochlear Pharmacokinetics – Impact of 3D Segmentation using Convolutional Neural Networks.” Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2020).
  • Forouzandeh, Farzad,  Zhu, Xiaoxia, Ahamed,  Nuzhet N.,  Walton, Joseph P., Frisina, Robert D., Borkholder, David A., "An Implantable, Refillable, And Scalable Microsystem For Chronic Murine Inner Ear Drug Delivery." Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2020).
  • Forouzandeh F. et al., "A Miniature Zero-power Plug-and-play Pump for Microfluidic Perfusion Applications." Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019.
  • Sanketh S. Moudgalya, Kevin Wilson, Xiaoxia Zhu, Mikalai M. Budzevich, Gary V. Martinez, Joseph P. Walton, Nathan D. Cahill, Robert D. Frisina, David A. Borkholder, “Cochlear Statistical Shape Modeling - Efficient Capture of Inter-Animal Scalae Variations.” Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2019).
  • Farzad Forouzandeh, Xiaoxia Zhu, Meng-Chun Hsu, Joseph P. Walton, Denis Cormier, Robert D. Frisina, David A. Borkholder, “Demonstration of a Wirelessly-Controlled Implantable Microsystem with Refillable Reservoir for Murine Inner Ear Drug Delivery.” Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2019).
  • Sanketh S. Moudgalya, Kevin Wilson, Xiaoxia Zhu, Mikalai M. Budzevich, Gary V. Martinez, Joseph P. Walton, Nathan D. Cahill, Robert D. Frisina, David A. Borkholder, “Cochlear Pharmacokinetics - Transport Parameter Learning and Forward Model Estimations of Intracochlear Drug Concentrations for Cochleostomy Infusions.” Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2019).
  • Farzad Forouzandeh, Xiaoxia Zhu, Ahmed Alfadhel, Meng-Chun Hsu, Joseph P. Walton, Denis Cormier, Robert D. Frisina, David Borkholder. "Murine Round Window Membrane Inner Ear Drug Delivery with a Wirelessly Controlled Implantable Micropump." Association for Research in Otolaryngology Midwinter Meeting, Baltimore, MD USA, 2018 February 9-13;
  • Forouzandeh F., Zhu X., Alfadhel A., Hsu M., Walton J.P., Cormier D., Frisina R.D., Borkholder D.A. “A Scalable 3D-Printed Fully Implantable Microsystem for Murine Inner Ear Drug Delivery with Wireless Control.” In Biomedical Engineering Society (BMES) Annual Meeting, Atlanta, GA. (2018).
  • Forouzandeh F, Borkholder DA. “A stand-alone implantable refillable scalable microreservoir for drug delivery in small animals.” In: Biomedical Engineering Society (BMES) Annual Meeting, Atlanta, GA. (2018).  
  • Sanketh S. Moudgalya, Kevin Wilson, Xiaoxia Zhu, Mikalai M Budzevich, Gary V Martinez, Robert D. Frisina, Joseph P. Walton, Nathan D. Cahill, David A. Borkholder. "Cochlear Pharmacokinetic Parameter Estimation - Impact of Localized 3D Image Registration and Reconstruction Noise." Association for Research in Otolaryngology (ARO) Midwinter meeting, February, 2018
  • Meng-Chun Hsu, Ahmed Alfadhel, Farzad Forouzandeh, David Borkholder. "Biocompatible Magnetic Nanocomposite Microcapsules as Highly Customizable Microfluidic One-way Diffusion Blocking Valves with Integrated Flow Sensing." Association for Research in Otolaryngology (ARO) Midwinter meeting, February, 2018
  • Ahmed Alfadhel, Jing Ouyang, Chaitanya Mahajan, Denis Cormier, David A. Borkholder. "Towards the Realization of Flexible and Wearable Microfluidic Electronics." KAUST-NSF Research Conference On Interactive Electronics, January 2017
  • Kevin Wilson, Sanketh S. Moudgalya, Zhenlin Xu, XiaoXia Zhu, Gary V. Martinez, Mikalai M. Budzevich, Robert D. Frisina, Joseph P. Walton, Nathan D. Cahill, David A. Borkholder. "Modeling and Extraction of Diffusion, Permeability and Clearance Parameters for Drug Delivery in the Murine Cochlea." Association for Research in Otolaryngology (ARO) Midwinter meeting, February, 2017
  • Ahmed Alfadhel, Meng Hsu, Farzad Forouzandeh, David A. Borkholder. "Magnetic Responsive Polyethylene Glycol Nanocomposite Actuators." Advances in Functional Materials (AFM), Los Angeles, USA, 14-17 August 2017
  • Jing Ouyang, Chaitanya Mahajan, Ahmed Alfadhel, Denis Cormier, David A. Borkholder. "Inkjet Printing of Polyethylene Glycol as a Sacrificial Material for Flexible Microsystems." Advances in Functional Materials (AFM), Los Angeles, USA, 14-17 August 2017
  • Farzad Forouzandeh, Kyle Smith, Meng-Chun Hsu, Chaitanya Mahajan, Jing Ouyang, Robert Carter, Xiaoxia Zhu, Bo Ding, Ahmed Alfadhel, Joseph P. Walton, Denis Cormier, Robert D. Frisina, David A. Borkholder. "An Implantable Peristaltic Micropump with Direct-Write-Printed Features for Inner Ear Drug Delivery under Wireless Control." Association for Research in Otolaryngology (ARO) Midwinter meeting, February, 2017
  • Jing Ouyang, Denis Cormier, Scott A Williams, David A. Borkholder. "Aerosol Jet Printing and Photonic Sintering of Lead Zirconate Titanate Films." Advances in Functional Materials (AFM), Los Angeles, USA, 14-17 August 2017
  • Farzad Forouzandeh, David A. Borkholder. "A Numerical Heat Transfer Analysis on a Fully Implantable Phase-Change Peristaltic Micropump." COMSOL Conference, Boston, USA, 2017
  • Kyle E. Smith, Tayler Swanson, S. Manian Ramkumar, Denis Cormier, Robert D. Frisina, David A. Borkholder. "Towards direct-write integrated electronics on 3D substrates – comparison of low temperature isotropic silver and anisotropic conductive adhesives for assembly of micropump control electronics." Association for Research in Otolaryngology Midwinter meeting, Feb 2016
  • Farzad Forouzandeh, Chaitanya Mahajan, Jing Ouyang, Robert Carter, Xiaoxia Zhu, Bo Ding, Lauren Mannix, Joseph P. Walton, Denis Cormier, Robert D. Frisina, David A. Borkholder. "A scalable peristaltic micropump with 3D-printed features and phase change actuation for inner ear applications." Association for Research in Otolaryngology Midwinter meeting, Feb 2016
  • Zhenlin Xu, Nathan D. Cahill, Gary V. Martinez, Mikalai M. Budzevich, Robert D.Frisina, Joseph P. Walton, David A. Borkholder. "3-D subject-atlas image registration for micro-computed tomography based characterization of drug delivery in the murine cochlea." Association for Research in Otolaryngology Midwinter meeting, Feb 2016
  • Alexander S. Liberson, Jeffrey S. Lillie, Praveen K. Koya, David A. Borkholder. "Simulation of wave propagation through the bifurcated compliant arterial network." Proceedings of the 2nd International Conference on Fluid Flow, Heat and Mass Transfer Ottawa, Ontario, Canada, April 30 – May 1, 2015 Paper No. 164
  • Borkholder DA, Duckworth J. "The Blast Gauge System Overpressure Thresholds – Present and Future." International State-of-the-Science Meeting on the Biomedical Basis for Mild Traumatic Brain Injury (mTBI) Environmental Sensor Threshold Values, 4-6 Nov (2014).
  • Kamimori GH, DaSilva U, Lee G, Kenyon M, Allpress K, Katselis G, Borkholder DA. "Laboratory and Field Validation of the Blast Gauge sensor system (BG) in Selected Operational Overpressure (OP) Scenarios." International State-of-the-Science Meeting on the Biomedical Basis for Mild Traumatic Brain Injury (mTBI) Environmental Sensor Threshold Values, 4-6 Nov (2014).
  • Zhu XX, Borkholder DA, Frisina RD. "Reduced concentration gradients in the murine cochlea utilizing novel round window membrane drug application techniques." Association for Research in Otolaryngology Midwinter meeting, Feb (2012).
  • Lillie, Jeffrey, Doran Mix, Karl Schwarz, Ankur Chandra, Steven Day, and David Borkholder. "Aortic Pulse Wave Velocity Does Not Correlate with Flow Wave Velocity or Mean Arterial Pressure in Robust, in Vitro Cardiovascular Hemodynamic Simulation." (2012): A184-A184.
  • Gladstone, M., Zhu, X., Luebke, A., Frisina, R.D., Borkholder, D.A. "Using micro-Computed Tomography to Assess Transport Parameters through Fluid Spaces of the Cochlea." Biomedical Engineering Society National Conference, University of Texas at Austin, October 6-9, (2010).
  • Johnson DG, Waldron MJ, Frisina RD, Borkholder DA. "Rodent Intracochlear Infusion Systems: Technology Advances for Implantable Micropumps." Association for Research in Otolaryngology Midwinter meeting, Feb (2010)
  • Zhu XX, Hyatt B, Frisina RD, Borkholder DA. "Flow Rate as a parameter for reducing concentration gradients in murine intracochlear infusion." Association for Research in Otolaryngology Midwinter meeting, Feb (2010).
  • Livingston, W.J., Zhu, X.X., Archilla, A.S., Frisina, R.D., Borkholder, D.A. "Intracochlear Infusions: A Surgical Approach to Reduce Concentration Gradients within the Cochlea." Association for Research in Otolaryngology Midwinter meeting, Feb (2009).
  • Hyatt, B.T., Archilla, A.S., Livingston, W.J., Zhu, X.X., Frisina, R.D., Borkholder, D.A. "Intracochlear Drug Delivery in the Mouse: Correlation of Simulated Concentration Gradients with Shifts in Measured Auditory Response." Association for Research in Otolaryngology Midwinter meeting, Feb (2009).
  • Johnson, D.G., Zhu, X., Frisina, R.D. and Borkholder, D.A. "Engineered Interface for Intracochlear Infusions in Small Rodents." ARO 2007 – 30th Annual Midwinter Meeting of the Association for Research in Otolaryngology, Denver, CO, February 10-15 (2007).

Patents

Patents

Invited Talks

Invited Talks

  • Ahmed Alfadhel, Jing Ouyang, Chaitanya Mahajan, Denis Cormier, David A. Borkholder. "Towards the Realization of Flexible and Wearable Microfluidic Electronics." KAUST-NSF Research Conference On Interactive Electronics, January 2017
  • David A. Borkholder. "Concept to Commercialization of a MEMS-based System- Having a Blast." Marquette University, April 14, 2015
  • David A. Borkholder. "Concept to commercialization of a MEMS-based blast dosimetry system." In 2015 Transducers-2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), pp. 281-286. IEEE, 2015.
  • David A. Borkholder. "Concept to Commercialization - Having a Blast." Keynote talk, RIT Albert J. Simone Innovation Series, Feb 28 (2013).
  • David A. Borkholder. "Micromachined Structures for Biological Studies." Invited talk, American Medical Writers Association Asilomar 2000 workshop, March 19-23 (2000).

Thesis

Thesis

  • Borkholder, David. "Cell based biosensors using microelectrodes." PhD diss., Stanford University, 1998. Open source