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Featured Project
Degenerative Disc Disease
Degenerative disc disease (DDD) is a major source of low back pain, which is not only the leading cause of activity limitation and work absence but also represents a tremendous financial burden to society. Dr. Wuertz-Kozak’s latest project, with incoming funding from NIH, aims to develop a novel, minimally-invasive approach for the treatment of DDD that relies on enhancing the regenerative and anti-inflammatory capacity of extracellular vesicles (EV) derived from mesenchymal stem cells using state-of-the-art gene editing technology. Successful completion of this study will guide future development of EV-based therapy not only for DDD, but for example also for osteoarthritis in the hands, neck, knees, and hips, which could benefit millions of people in the United States every year.
Karin Wuertz-Kozak, Principal Investigator
Additional information about Dr. Wuertz-Kozak’s research can be found at https://www.rit.edu/wuertzlab. In addition, Dr. Wuertz-Kozak is active on Twitter – follow her at @Wuertz-Lab.
News
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September 29, 2023
![a crowd watching as a woman stands looking surprised next to two men making an announcement in front of a building in Ethiopia.]()
RIT/NTID audiologist ensures deaf, hard-of-hearing children in Ethiopia receive essential services
For nearly a decade, RIT audiologist Catherine Clark has been volunteering in Ethiopia, providing essential services to the country’s deaf and hard-of-hearing children. As a result of her efforts, Clark was recognized recently with the naming of a new audiology lab in her honor.
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September 1, 2023
![two researchers standing next to each other in a lab.]()
RIT researchers pioneer solutions for degenerative disc disease and back pain
Researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S. Using state-of-the-art gene editing technology in mesenchymal stem cells, the researchers will add to the growing field of regenerative medicine, the process of producing cellular therapies to alleviate pain and lack of mobility.
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August 15, 2023
![screen shot of the Project Rose prototype home page, with four boxes, two of which show an icon with a sunset and the words feel better now, and the other with a mountain range icon and the words make a durable change.]()
RIT professors combine interactive media and hypnosis to ease pain
Researchers from RIT and University of Washington are harnessing the power of interactive media and clinical hypnosis to help people manage pain without drugs. The team has received a National Institutes of Health (NIH) grant for the work.
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July 20, 2023
![person wearing P P E and using a microscope. There are graphics of medical icons and strands of D N A overlayed on the photo.]()
AI has secured a footing in drug discovery. Where does it go from here?
PharmaVoice talks to David Longo ’10 (computational mathematics), CEO of drug design company Ordaos, about artificial intelligence in drug development.
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