Michael Schrlau Headshot

Michael Schrlau

Associate Professor

Department of Mechanical Engineering
Kate Gleason College of Engineering
mgseme@rit.edu
585-475-2139
Office Location
ENG-2549

Michael Schrlau

Associate Professor

Department of Mechanical Engineering
Kate Gleason College of Engineering

Education

BS, University of Pittsburgh; Ph.D., University of Pennsylvania

Bio

Dr. Schrlau is interested in several aspects critical to the interface of nanotechnology and biology, including nanomanufacturing, nanomanipulation, technology-biology interactions, and biomedical applications, and investigates micro/nanoscalefluid behavior and develops related micro/nanotechnologies for biological metrology. Dr. Michael Schrlau earned his B.S. in Mechanical Engineering and Materials Science from the University of Pittsburgh in From 1998 to 2004, he worked for Kimberly-Clark Corp in roles ranging from R&D engineering to operations management. In 2009, he earned his Ph.D. in Mechanical Engineering and Applied Mechanics at the University of Pennsylvania for his research on carbon-based biological nanoprobes. After completing a postdoctoral fellowship in the Department of Pharmacology at Temple University, he joined the Department of Materials Science and Engineering at Drexel University as a Research Assistant Professor in November 2009, where he led the research activities of the W. M. Keck Institute. During the same time, Dr. Schrlau was also an adjunct lecturer at the University of Pennsylvania in the Department of Materials Science and Engineering. His research appears in several high impact journals, including Nature Nanotechnoloy, ACS Nano, Small, and Nanotechnology, was featured in Nanotechnology (cover image) and ACS Nano, and has resulted in several patents. Dr. Schrlau actively supports graduate and undergraduate research and is active in nanotechnology K-12 outreach. He is founding director of the Nano-Bio Interface Laboratory (NBIL) at the Rochester Institute of Technology. For more about Dr. Schrlau see his website.

Selected Publications

Orynbayeva Z, Singhal R, Vitol EA, Schrlau MG, Papazoglou E, Friedman G, Gogotsi Y. Physiological validation of cell health upon probing with carbon nanotube endoscope and its benefit for cell interrogation. (2011) Nanomedicine DOI:10.1016/j.nano.2011.08.008

Nui JJ, Schrlau MG, Friedman G, Gogotsi Y. Carbon nanotube-tipped endoscope for in situ intracellular surface-enhanced Raman spectroscopy. (2011) Small 7:540-545.

Singhal R, Orynbayeva Z, Sundaram RVK, Niu JJ, Bhattacharyya S, Vitol E, Schrlau MG, Papazoglou E, Friedman G, Gogotsi Y. (2011) Multifunctional nanotube-based cellular endoscopes. Nature Nanotechnology 6:57-64.

Thompson JA, Du X, Grogan JM, Schrlau MG, Bau HH. (2010) Polymeric microbead arrays for microfluidic applications. J Micromech Microeng 20:115017 (8pp).

Schrlau MG, Bau HH. (2010) The application of carbon nanopipettes in bionanotechnology. J Assoc Lab Automation 15:145-151. (Invited review article for special issue on bionanotechnology, April 2010)

Nguyen VD, Schrlau MG, Tran SBQ, Bau HH, Ko HS, Byun D. (2009) Fabrication of nanoscale nozzle for electrohydrodynamic (EHD) inkjet head and high precision patterning by drop-on-demand operation. J Nanosci Nanotechnol 9:7298-7302.

Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S. (2009) Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. J Cell Biol 186:201-209.

Liu C, Schrlau MG, Bau HH. (2009) Single bead-based electrochemical biosensor. Biosens Bioelectron 25:809-814.

Schrlau MG, Bau HH. (2009) Carbon-based nanoprobes for cell biology. Microfluid Nanofluid 7:439-451. (Invited review article)

Vitol EA, Schrlau MG, Bhattacharyya S, Ducheyne P, Bau HH, Friedman G, Gogotsi Y. (2009) Effects of deposition conditions on the structure and chemical properties of carbon nanopipettes. Chem Vapor Depos 15:204-208

mgseme@rit.edu
585-475-2139

Select Scholarship

Journal Paper
Scheibel, OV and MG Schrlau. "A Self‐Contained Two‐Electrode Nanosensor for Electrochemical Analysis in Aqueous Microenvironments." Electroanalysis 32. (2020): 1914-1921. Web.
Hensel, NC, RM Dunn, and MG Schrlau. "Computerized control system and interface for flexible micromanipulator control." Advances in Engineering Software 86. (2015): 107-114. Print.
Arowosola, A., et al. "Fabrication of theta carbon nanopipettes using a template-based chemical vapor deposition nanomanufacturing process." Journal of Multidisciplinary Engineering Science and Technology 2. (2015): 896-901. Print.
Golshadi, M., et al. "Effects of synthesis parameters on carbon nanotubes manufactured by template-based chemical vapor deposition." Carbon 80. (2014): 28-39. Print.
Orynbayeva, Z., et al. "Physiological validation of cell health upon probing with carbon nanotube endoscope and its benefit for cell interrogation." Nanomedicine: Nanotechnology, Biology, and Medicine 8. (2012): 590-598. Print.
Nui, JJ, et al. "Carbon nanotube-tipped endoscope for in situ intracellular surface-enhanced Raman spectroscopy." Small 7. (2011): 540-545. Print.
Singhal, R., et al. ") Multifunctional nanotube-based cellular endoscopes." Nature Nanotechnology 6. (2011): 57-64. Print.
Thompson, JA, et al. "Polymeric microbead arrays for microfluidic applications." J Micromech Microeng 20. (2010): 115017. Print.
Schrlau, MG and HH Bau. "The application of carbon nanopipettes in bionanotechnology." J Associate Lab Automation. 15 (2010): 145-151. Print.
Nguyen, VD, et al. "Fabrication of nanoscale nozzle for electrohydrodynamic (EHD) inkjet head and high precision patterning by drop-on-demand operation." J Nanosci Nanotechnol 9. (2010): 7298-7302. Print.
Liu, C., MG Schrlau, and HH Bau. "Single bead-based electrochemical biosensor." Biosens Bioelectron 25. (2009): 809-814. Print.
Schrlau, MG and HH Bau. "Carbon-based nanoprobes for cell biology." Microfluid Nanofluid 7. (2009): 439-451. Print.
Vitol, EA, et al. "Effects of deposition conditions on the structure and chemical properties of carbon nanopipettes." Chem Vapor Depos 15. (2009): 204-208. Print.
Schrlau, MG, NJ Dun, and HH Bau. "Cell electrophysiology with carbon nanopipettes." ACS Nano 3. (2009): 563-568. Print.
Schrlau, MG, et al. "Carbon nanopipettes characterize calcium release pathways in breast cancer cells." Nanotechnology 19. (2008): 325102. Print.
Schrlau, MG, et al. "Carbon nanopipettes for cell probes and intracellular injection." Nanotechnology 19. (2008): 15101. Print.
Golshadi, Masoud, et al. "Effects of Synthesis Parameters on Carbon Nanotubes Manufactured by Template-based Chemical Vapor Deposition." Carbon 80. (2014): 28-39. Print.
Orynbayeva, Z, et al. "Physiological Validation of Cell Health Upon Probing with Carbon Nanotube Endoscope and its Benefit for Cell Interrogation." Nanomedicine. (2012): 1-10. Print.
Nui, J.J., et al. "Carbon Nanotube-tipped Endoscope for in Situ Intracellular Surface-enhanced Raman Spectroscopy." Small 7. (2011): 540-545. Print.
Singhal, R., et al. "Multifunctional Nanotube-based Cellular Endoscopes." Nature Nanotechnology 6. (2011): 57-64. Print.
Provisional Patent
Bau, Haim H. and Michael G. Schrlau. "Multiplexed Nanoscale Electrochemical Sensor for Multi-analyte Detection." Patent US 8,877,518 B2. 4 Nov. 2014.
Book Chapter
Schrlau, Michael and Masoud Golshadi. "Carbon Nanostructures in Biomedical Applications." Carbon Nanomaterials. Ed. Rudiger Klingeler and Robert B. Sim. Heidelberg, Germany: Elsevier, 2012. Print.
Schrlau, M. G. "Carbon Nanotube-based Sensors." Comprehensive Biomaterials, Elsevier. tbd, tbd: In Review, 2011. 1-10. Print.
Schrlau, M. G. and H. H. Bau. "Probing Cells with Nanotechnology." Microfluidics and Nanofluidics Handbook: Fabrication, Implementation and Applications,. Florence, KY: Taylor and Francis, LLC, 2011. 1-10. Print.
Published Conference Proceedings
Golshadi, Masoud and Michael Schrlau. "Template-Based Synthesis of Aligned Carbon Nanotube Arrays for Microfluidic and Nanofluidic Applications." Proceedings of the 222th Electrochemical Society Fall 2012 Meeting (PRIME). Ed. ECS. Honolulu, HI: n.p., 2012. Print.
Hensel, Nicholas and Michael Schrlau. "Computer Controlled Actuation of Micro-Manipulator via Serial Port with MATLAB GUI." Proceedings of the 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'12). San Diego, CA: n.p., 2012. Print.

Currently Teaching

CHEM-493
Chemistry Research
1 - 3 Credits
This course is a faculty-directed student project or research in chemistry that could be considered of an original nature.
CHEM-495
Advanced Chemistry Research
1 - 3 Credits
This course is a faculty-directed student project or research involving laboratory work, computer modeling, or theoretical calculations that could be considered of an original nature. The level of study is appropriate for students in their final two years of study.
MECE-210
Fluid Mechanics I
3 Credits
This course investigates the physical characteristics of a fluid: density, stress, pressure, viscosity, temperature, vapor pressure, compressibility. Descriptions of flows include Lagrangian and Eulerian; stream-lines, path-lines and streak-lines. Classification of flows include fluid statics, hydrostatic pressure at a point, pressure field in a static fluid, manometry, forces on submerged surfaces, buoyancy, standard and adiabatic atmospheres. Flow fields and fundamental laws are investigated including systems and control volumes, Reynolds Transport theorem, integral control volume analysis of basic equations for stationary and moving control volumes. Inviscid Bernoulli and the Engineering Bernoulli equation are utilized when analyzing fluid systems. Other concepts studied include incompressible flow in pipes; laminar and turbulent flows, separation phenomenon, dimensional analysis.
MECE-689
Grad.Lower Level Special Topic
1 - 3 Credits
Topics and subject areas that are not regularly offered are provided under this course. Such courses are offered in a normal format; that is, regularly scheduled class sessions with an instructor.

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