AB, Oberlin College; Ph.D., Massachusetts Institute of Technology
My research work is primarily in biological physics. In our lab we conduct experimental and theoretical studies of phase transitions, solution phase properties and critical phenomena in a variety of complex fluids. I am particularly interested in the physical and chemical aspects of protein condensation diseases, including cataract and sickle cell disease.
We employ the techniques of quasielastic and static light scattering, x-ray scattering, neutron scattering, nuclear magnetic resonance, and Monte Carlo simulation to study protein mixtures, intrinsically disordered peptides, micelles, microemulsions, and other biological polymers.
Current experimental projects include studies of solutions of eye lens crystallin proteins and their mixtures, of the biological polymer, hyaluronate, and of mixtures that include the peptide, protamine. Another current project is to develop theory and methods for combining polarized neutron scattering and nuclear magnetic resonance in the same instrument, which has the potential to greatly refine probabilistic structural information about macromolecular liquids. We are also developing models of charge regulation-mediated interactions between proteins, and developing light scattering theory and methods for noninvasive measurement of the Gibbs free energies of mixing of liquid mixtures.
In the News
August 27, 2018
Inclusive Excellence cultivates diversityThe first Inclusive Excellence research fellowship was held this summer and paired seven undergraduate students in the College of Science with research mentors. The initiative is working to create a deeper understanding of diversity in the College of Science and at RIT.