Renata Rezende Miranda
Post Doctoral Researcher
Renata Rezende Miranda
Post Doctoral Researcher
Education
BS, Federal University of Ouro Preto, Brazil; MS, Federal University of Minas Gerais, Brazil; Ph.D., University of Southern California
Bio
I'm a chemist/pharmacist with expertise in organic synthesis of small molecules, medicinal chemistry, and chemical biology. My main research interests involve using chemistry tools to probe and understand biological processes and apply this knowledge to the development of new drugs.
I received a Ph.D. in Chemistry from the University of Southern California (USC) in 2021. At USC, I worked with structure-based design, synthesis, and biological evaluation of covalent small-molecule inhibitors and clickable probes targeting oncogenic protein kinases from the Fibroblast Growth Factor Receptor (FGFR) subfamily.
In Fall 2021, I started as a Postdoctoral Research Associate at the Rochester Institute of Technology (RIT) working with Prof. André Hudson. My research now focuses on the development of chemical biology and genomic approaches to study antimicrobial resistance mechanisms, as well as on the discovery of antibiotic compounds produced by various bacterial species.
Select Scholarship
Mozrall, A.R., Miranda, R.R., Kumar, G., Wadsworth, C.B., Hudson, A.O. Isolation, whole-genome sequencing and annotation of two antibiotic producing and resistant bacteria, Enterobacterroggenkampii sp RIT 834 and Acinetobacter pittii sp RIT 835 from disposable masks collected from the environment. (2022) Microbiol. Resour. Announc. 12:e0075722. Access here.
Parthasarathy, A.; Miranda, R.R.; Eddingsaas, N.C.; Chu, J.; Freezman, I.M.; Tyler, A.C.; Hudson, A.O. Polystyrene Degradation by Exiguobacterium sp. RIT 594: Preliminary Evidence for a Pathway Containing an Atypical Oxygenase. (2022) Microorganisms, 10, 1619. Access here.
Renata Rezende Miranda & Chao Zhang. Reactivity-Based Chemical-Genetic Study of Protein Kinases. (2022) RSC Med. Chem. 13, 783-797. Access here.
Miranda, R.R., Parthasarathy, A., Hudson A.O. Exploration of chemical biology approaches to facilitate the discovery and development of novel antibiotics. (2022) Front. Trop. Dis. 3:845469. Access here.
Schroeter, M.N., Gazali, S.J., Parthasarathy, A., Wadsworth, C.B., Miranda, R.R., Hudson, A.O. Isolation, whole-genome sequencing and annotation of three unclassified antibiotic-producing bacteria, Enterobacter sp. RIT 637, Pseudomonas sp. RIT 778 and Deinococcus sp. RIT 780. (2021) Microbiol. Resour. Announc. 10(48):e00863–21. Access here.
Renata Rezende Miranda, Ying Fu, Xiaojuan Chen, John Perino, Ping Cao, John D. Carpten, Yongheng Chen, & Chao Zhang. Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma. J. Med. Chem. 2020, 63, 11484−11497. Access here.
Assadieskandar, A., Rezende Miranda, R., Broyer, R. M. Visually Tracking of Acid-Base Extractions Using Colorful Compounds. J. Chem. Educ. 2020, 97, 1402−1405. Access here.