Suzanne O'Handley Headshot

Suzanne O'Handley

Associate Professor
School of Chemistry and Materials Science
College of Science

585-475-2751
Office Location

Suzanne O'Handley

Associate Professor
School of Chemistry and Materials Science
College of Science

Education

BS, Rutgers University; MS, Ph.D., University of Rochester

585-475-2751

Areas of Expertise

Currently Teaching

CHEM-790
1 - 6 Credits
Dissertation research by the candidate for an appropriate topic as arranged between the candidate and the research advisor.
CHMB-495
1 - 3 Credits
This course is a faculty-directed student project or research involving laboratory work, computer modeling, or theoretical calculations that could be considered of an original nature. The level of study is appropriate for students in their final two years of study.
CHMB-493
1 - 3 Credits
This course is a faculty-directed student project or research in biochemistry that could be considered of an original nature.
CHMB-402
3 Credits
This course introduces the structure and function of biological macromolecules and their metabolic pathways. The relationship between the three-dimensional structure of proteins and their function in enzymatic catalysis will be examined. Membrane structure and the physical laws that apply to metabolic processes will also be discussed.
CHMB-704
3 Credits
This course will cover nucleic acid structures as determined by NMR and X-ray crystallography and nucleic acid catalysis, especially that of ribozymes. Genomics, specifically whole-genome sequencing papers, will be analyzed. Current RNA topics including the RNA World, Ribozymes, RNAi, and Riboswitches will be discussed. Current DNA topics including Lateral/Horizontal DNA Transfer, Genome Duplication, Alternate Gene Expression and Synthetic Life will also be discussed.
CHMG-146
1 Credits
The course combines hands-on laboratory exercises with workshop-style problem sessions to complement the CHMG-142 lecture material. The course emphasizes the use of experiments as a tool for chemical analysis and the reporting of results in formal lab reports. Topics include the quantitative analysis of a multicomponent mixture using complexation and double endpoint titration, pH measurement, buffers and pH indicators, the kinetic study of a redox reaction, and the electrochemical analysis of oxidation reduction reactions.
CHMB-610
3 Credits
This course analyzes protein structure function relationships. Students will investigate how proteins function and how the structure relates to that function. The principles that explain enzyme rate enhancements and mechanistic enzymology will be examined. Additionally, protein superfamilies for phylogenetic relationships will be explored to enhance understanding of protein structure-function relationships. Students will read and discuss the current scientific literature and classic papers.
BIOL-460
3 Credits
This course is an introduction to the probabilistic models and statistical techniques used in computational molecular biology. Examples include Markov models, such as the Jukes-Cantor and Kimura evolutionary models and hidden Markov models, and multivariate models use for discrimination and classification.
CHMB-460
3 Credits
This course investigates the mechanisms of pathogenesis of bacterial, viral, and other microbial infectious agents. This course also covers the historical, social, and cultural impact that these infectious diseases have had on society. Topics may include: antibiotics and antibiotic resistance, vaccines, gut microflora and health, foodborne illnesses, bioterrorism, HIV, tuberculosis, malaria, and staph infections.
CHMB-405
3 Credits
An introduction to the theory and practice of modern experimental biochemical laboratory techniques and concepts. The weekly two-hour lecture provides a theoretical framework for the course and includes a discussion of the properties of biomolecules and how those properties are exploited in the separation and characterization of the molecules. Practical laboratory techniques include the preparation of buffers, centrifugation, chromatography, electrophoretic methods, and UV-visible spectrophotometry as applied to the isolation and characterization of proteins and nucleic acids. The manipulation of genetic material in E. coli will also be executed. This course will be offered in a writing intensive format where the students will write and submit the different sections found in scientific papers (abstract, introduction, materials and methods, results, discussion, conclusions, references, figures, tables) in an iterative fashion that will include regular feedback from the instructor.

Latest News

  • March 13, 2019

    Head-and-shoulders view of researcher wearing maroon top and cardigan

    RIT Associate Professor Suzanne O’Handley nationally recognized for mentorship

    RIT Associate Professor Suzanne O’Handley has been selected by the Council on Undergraduate Research and the Goldwater Scholarship Foundation as the 2019 CUR-Goldwater Scholars Faculty Mentor Awardee. O’Handley, a faculty member in RIT’s School of Chemistry and Materials Science, was chosen from 10 finalists for her considerable achievements as a dynamic scholar, teacher and mentor.

Select Scholarship

Journal Paper
O'Handley, Suzanne F., et al. "Insights into the Substrate Specificity of the MutT Pyrophosphohydrolase using Structural Analogues of 8-Oxo-2'-Deoxyguanosine Nucleotide." Bioorg Medical Chem Lett. 26. 8 (2016): 2014--2017. Print.
O'Handley, Suzanne F., et al. "Kinetic and Mutational Studies of the Adenosine Diphosphate Ribose Hydrolase from Mycobacterium Tuberculosis." J Bioenerg Biomembr. 48. 6 (2016): 557--567. Print.