Life Sciences Seminar: Microbial Messages, Human Lessons: What Archaea Teach Us About Communication
Life Sciences Seminar
Microbial Messages, Human Lessons: What Archaea Teach Us About Communication
Dr. Mecky Pohlschroder
Professor of Biology
University of Pennsylvania
Abstract:
Archaea are critical players in global biogeochemical cycles, and important members of human-associated microbiomes. Yet fundamental aspects of their cell biology, such as cell–cell communication, remain poorly understood. While quorum sensing (QS), a population-density-dependent form of microbial communication, is widespread in bacteria, little is known about analogous processes in archaea. We have developed Haloferax volcanii as the first robust archaeal model for QS studies and revealed that this communication controls specific behaviors like cell movement and shape. Furthermore, we have started to characterize the genes and proteins involved in this process and could show that archaeal QS likely participates in interspecies, as well as interdomain, communication. This research also highlights that just like archaea, science thrives on communication and connection. It is a reminder to nurture collaborations and communities beyond the lab. Like microbes, we thrive when we connect.
Intended Audience:
Beginners, undergraduates, graduates. Those with interest in the topic.
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